Which symptom does Duchenne Muscular Dystrophy typically exhibit?

Duchenne Muscular Dystrophy (DMD) is characterized by progressive muscle weakness, which is a hallmark symptom of the condition. This progressive aspect means that the muscle weakness worsens over time, impacting mobility and function as the individual ages. DMD primarily affects skeletal muscles, leading to a decline in muscle function and the ability to perform daily activities.

Initially, muscle weakness may present subtly, but over time it becomes more pronounced, particularly in the proximal muscles of the hips, thighs, and shoulders. This deterioration in strength is due to the progressive degeneration of muscle fibers, which is intrinsic to the pathology of DMD. As the disease advances, individuals may experience significant difficulties in mobility, such as walking, climbing stairs, and eventually achieving independence.

In contrast, slight muscle weakness would not adequately encompass the severity or progressive nature of DMD, uncontrolled movements do not characterize this condition, and joint stiffness is not a primary symptom. Therefore, the emphasis on progressive muscle weakness accurately reflects the core impact of Duchenne Muscular Dystrophy on affected individuals.